Applied Mathematics → Agentic AI

Mohsen Sadr

Applied mathematician building physics-based agentic AI that delivers solutions for the fusion energy and space industries.

Portrait of Mohsen Sadr
Built at / with
PAI Dynamics MIT Paul Scherrer Institute EPFL RWTH Aachen

About

I'm an applied mathematician and the founder of PAI Dynamics, building physics-based agentic AI that delivers solutions for the fusion energy and space industries.

Before founding the startup, I spent a decade building high-performance simulation and machine-learning software at MIT, the Paul Scherrer Institute, and the Swiss Plasma Center (EPFL) for national research programs.

News

2025 – 2026
  • Jul2026

    PAI Dynamics wins Venture Kick Stage 1

    Awarded CHF 10,000 in Stage 1 of Venture Kick, Switzerland's leading start-up support programme, to help advance our physics-based agentic AI platform for fusion energy and space design.

  • Jul2026

    New preprint: ORB5X, built with Agentic AI

    “ORB5X v1.0: a performance-portable global electromagnetic gyrokinetic PIC code in C++/Kokkos built using Agentic AI” is now on arXiv. A modern C++17/Kokkos rewrite of ORB5, developed at PAI Dynamics with PhysicsCode and delivered to the Swiss Plasma Center and Max Planck Institute.

  • Jun2026

    EuroHPC compute grant

    ORB5X received its first EuroHPC Joint Undertaking allocation: 8,600 node-hours across five European systems — Leonardo BOOSTER, LUMI-G, MareNostrum5 ACC, Karolina GPU, and Discoverer.

  • Feb2026

    PSI Founder Fellowship for Physics-based AI Platform

    Awarded a PSI Founder Fellowship (up to CHF 150,000) to develop an AI-based platform that accelerates and reduces the cost of physical simulations for fusion energy and space technologies.

Selected work

03 shipped

PhysicsCode

A physics-aware agentic coding assistant for simulation and engineering software. It pairs frontier LLMs with domain knowledge of numerical methods, solver architectures, and HPC codebases — so scientists and engineers can iterate on simulation code through natural-language prompts.

ORB5X

A performance-portable rewrite of the ORB5 gyrokinetic particle-in-cell code in modern C++17 with Kokkos — global, electromagnetic, multi-species, for first-principles simulation of turbulence, transport, and energetic-particle dynamics in toroidal plasmas. Portable from laptops to NVIDIA/AMD GPU supercomputers.

Non-equilibrium multiphase flows

A stochastic process for short- and long-range interactions of monatomic particles that satisfies the kinetic equation up to desired moments, with cost scaling linearly in particle count. Implemented in PICLas.

Career

2013 – present

Experience

  • Founder
    2026 –
  • Founder Fellow
    2026 –
  • Research Affiliate
    2025 –
  • Scientist
    2023–25
  • Fellow
    2021–23
  • Scientific Collaborator
    2020–21

Education

  • PhD, Applied & Computational Mathematics
    2020
  • MSc, Simulation Sciences
    2017
  • BSc, Mechanical Engineering
    2013

Grants & awards

  • 8,600 hEuroHPC JU compute allocation for ORB5X, 2026
  • CHF 10kVenture Kick Stage 1, PAI Dynamics, 2026
  • CHF 100kPSI / QBIT Capital Founder Fellowship, 2026
  • €1.2mEUROfusion / SNSF consortium project, 2021
  • €100kWalter Benjamin scholarship, German Research Foundation (DFG), 2020

Publications

18 papers
Simulation of plasma / fluid
  • 01

    Sadr, Lanti, Mishchenko, Wang, Villard — “ORB5X v1.0: a performance-portable global electromagnetic gyrokinetic PIC code in C++/Kokkos built using Agentic AI”

    2026

  • 02

    Sadr, Mishchenko, Hayward-Schneider, Koenies, Bottino, Biancalani, Donnel, Lanti, Villard — “Linear and nonlinear excitation of TAE modes by external electromagnetic perturbations using ORB5”

    Plasma Physics and Controlled Fusion, 64, 085010 · 2022

  • 03

    Donnel, Cazabonne, Villard, Brunner, Coda, Decker, Murugappan, Sadr — “Quasilinear treatment of wave–particle interactions in the electron cyclotron range and its implementation in a gyrokinetic code”

    Plasma Physics and Controlled Fusion, 63, 064001 · 2021

  • 04

    Farazi, Sadr, Kang, Schiemann, Vorobiev, Scherer, Pitsch — “Resolved simulations of single char particle combustion in a laminar flow field”

    Fuel, 201, 15–28 · 2017

Modelling in kinetic theory
  • 05

    Mies, Sadr, Torrilhon — “An efficient jump-diffusion approximation of the Boltzmann equation”

    Journal of Computational Physics, 490, 112308 · 2023

  • 06

    Sadr, Pfeiffer, Gorji — “Fokker–Planck–Poisson kinetics: multi-phase flow beyond equilibrium”

    Journal of Fluid Mechanics, 920, A46 · 2021

  • 07

    Sadr, Wang, Gorji — “Coupling kinetic and continuum using data-driven maximum entropy distribution”

    Journal of Computational Physics, 444, 110542 · 2021

  • 08

    Sadr, Gorji — “Treatment of long-range interactions arising in the Enskog–Vlasov description of dense fluids”

    Journal of Computational Physics, 378, 129–142 · 2019

  • 09

    Sadr, Gorji — “A continuous stochastic model for non-equilibrium dense gases”

    Physics of Fluids, 29, 122007 · 2017

Variance reduction
  • 10

    Windhab, Adelmann, Sadr — “VR-PIC: an entropic variance-reduction method for particle-in-cell solutions of the Vlasov–Poisson equation”

    2026

  • 11

    Sadr, Hadjiconstantinou — “A variance-reduced direct Monte Carlo simulation method for solving the Boltzmann equation over a wide range of rarefaction”

    Journal of Computational Physics, 472, 111677 · 2023

  • 12

    Sadr, Hadjiconstantinou — “Variance reduced particle solution of the Fokker–Planck equation with application to rarefied gas and plasma dynamics”

    Journal of Computational Physics, 492, 112402 · 2023

Data-driven modelling
  • 13

    Sadr, Tohme, Youcef-Toumi — “Data-driven discovery of PDEs via the adjoint method”

    Transactions on Machine Learning Research · 2025

  • 14

    Tohme, Sadr, Youcef-Toumi, Hadjiconstantinou — “MESSY estimation: maximum-entropy based stochastic and symbolic density estimation”

    Transactions on Machine Learning Research · 2023

  • 15

    Sadr, Torrilhon, Gorji — “Gaussian process regression for maximum entropy distribution”

    Journal of Computational Physics, 418, 109644 · 2020

Optimal transport
  • 16

    Sadr, Gorji — “Collision-based dynamics for multi-marginal optimal transport”

    2024

  • 17

    Sadr, Mohajerin Esfehani, Gorji — “Optimal transportation by orthogonal coupling dynamics”

    2024

  • 18

    Sadr, Hadjiconstantinou, Gorji — “Wasserstein-penalized entropy closure: a use case for stochastic particle methods”

    Journal of Computational Physics · 2024

Talks & teaching

2017 – 2026

Talks

  • TSVV10 Meeting
    EUROfusion, online
    Jul 2026
  • Particles, Flows & Maps for Sampling Complex Distributions
    Lausanne, Switzerland poster
    Nov 2025
  • 5th Mathematical & Scientific Machine Learning
    Naples, Italy poster
    Aug 2025
  • 30th Biennial Numerical Analysis Conference
    Glasgow, UK talk
    Jun 2025
  • Swiss Plasma Center
    EPFL — invited seminar
    Apr 2025
  • CSD Scientific Retreat
    Paul Scherrer Institute — invited talk
    Mar 2024
  • Machine Learning Seminar Series
    Paul Scherrer Institute — invited talk
    Apr 2024
  • Symposium of Center for Computational Science & Technology
    MIT — invited talk
    Mar 2023
  • 4th Mathematical & Scientific Machine Learning
    Providence, USA poster
    Jun 2023
  • 19th European Fusion Theory Conference
    Virtual poster
    Oct 2021
  • Swiss Plasma Center
    EPFL — invited seminar
    Apr 2020
  • 9th Int'l Congress on Industrial and Applied Mathematics
    Valencia, Spain poster
    Jul 2019
  • 10th Int'l Conference on Multiphase Flow
    Rio de Janeiro, Brazil talk
    May 2019
  • Mathematics Institute of Computational Science and Engineering (MATHICSE)
    EPFL — invited seminar
    Jul 2019
  • 3rd European Conference on Non-Equilibrium Gas Flows
    Strasbourg, France talk
    Feb 2018
  • Institute of Fluid Dynamics
    ETH Zurich — invited seminar
    May 2018
  • Institute of Fluid Dynamics
    ETH Zurich — invited seminar
    Aug 2017

Teaching

  • Introduction to Computational Physics
    ETH Zurich — Monte Carlo methods · slides
    '23–24
  • Computational Statistical Physics
    ETH Zurich — rarefied gas & plasma · slides
    '24
  • Computational Physics 1 & 2
    EPFL — advection-diffusion, chaotic systems
    '20–21
  • Mathematical Foundations 1–5
    RWTH Aachen — numerical methods, linear algebra
    '17–19

Peer review

Let's talk

Building physics simulation for the age of agentic AI.

mohsen.sadr@icloud.com